The Identification of 2-dimethylamino-6- Hydroxypurine and Its Ribonucleoside in Urine of Normal and Leukemic Subjects.
نویسندگان
چکیده
Urine from normal and leukemic subjects on controlled low-purine diets was frac tionated by ion-exchange column chromatography, and the various effluent peaks exhibiting absorbance at 260 m/i were subjected to two-dimensional filter paper chromatography for further resolution. It appeared from gross examination of the chromatograms that there were a greater number and concentration of blue fluorescent substances in much of the leukemic urine. Two of these compounds have been identi fied as 2-dimethylamino-6-hydroxypurine and its ribonucleoside.
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عنوان ژورنال:
- Cancer research
دوره 23 شماره
صفحات -
تاریخ انتشار 1963